- Monitoring Physical Activity and Fitness
- Health-related fitness tests for public health monitoring
- Development and evaluation of a 2-km Walking Test
- Health-related fitness test battery
- Health-related fitness tests for older adults
- Required motor abilities in commonly practised exercise modes
- Physical activity and motor abilities
- Health 2000 and Health 2011
- Exercise Loading and Bone Structure
- KidsOut! — promoting physical activity and reducing sedentary behavior among 8th graders
- Physical Activity as a Medicine
- Counselling, lifestyle and physical activity in maternity care -study (NELLI)
- Effect of physical activity on menopausal symptoms
- Breast Cancer and Exercise
- KÄPY Research – Social Ecological Intervention to Promote Active Commuting to Work
- Prevention of Chronic Low Back Pain in Female Nurses
- Weight Reduction and Long-distance Truck and Bus Drivers
- Physical Activity and Reducing of Headaches
- Developing physical activity counselling
- VESOTE Effective Life-style Counselling for Social and Health Care
- Safety of Physical Activity
- Predictors of Lower Extremity Injuries in Team Sports PROFITS
- Risk Factors of Injuries and Injury Prevention in Youth Football
- Floorball Injuries – Epidemiology and Prevention
- Neuromuscular Exercise and Counseling Prevent Low Back Pain
- Effects of Exercise on Physical Functioning, Bone Strength and Fall Risk among Older Women
- Vitamin D and Exercise in Fall Prevention
- Effect of Vibration Training on Physical Functioning and Risk of Falling in Older People
- Fall-induced Injuries Among Older Adults in Finland
- LiVE: Sports and Exercise Safety Program in Finland
- KaatumisSeula: Implementation of Evidence-Based Fall Prevention for Communities
- Recent Presentations in Conferences
- WHO Europe HEPA Collaboration
Breast Cancer and Exercise
This national multi-center randomized controlled clinical trial (BREX, NCT00639210) explores the health benefits of exercise training among breast cancer survivors.Lisää sisältö
Breast cancer is the most common cancer type among women with nearly 3,800 new women diagnosed in Finland every year. In addition to benefits, the adjuvant treatments of breast cancer can also lead to bone loss and reduced physical and mental performance. Exercise, in turn, has apparent potential to prevent these harmful consequences, but this has not yet been consistently shown among breast cancer survivors in an adequate-powered trial.
The BREX trial aimed to investigate the effects of one-year intensive aerobic exercise on various health outcomes, including bone mineral density (BMD), physical performance, and quality of life (QoL).
Almost 500 breast cancer survivors aged 35 - 68 years were recruited in the BREX trial from three university hospitals (Helsinki, Tampere and Turku) and they were randomly assigned either into training or control group. The trial comprised one-year training randomized controlled intervention and follow-up assessments at 3, 5, and 10 years (completed in 2018). Feasibility of the planned training program, including jumping exercises and circuit training, was evaluated in a pilot study. The exercise group was asked to participate in supervised training once a week and do home training three times a week.
On average, training including jumping was performed 2.2 times a week among premenopausal women and 2.7 times a week among postmenopausal women. One-year exercise training completely prevented femoral neck bone loss in premenopausal patients, whereas no treatment effect on BMD was seen in postmenopausal women. Neuromuscular performance improved among the trainees compared to controls. Cardiovascular fitness improved similarly in both groups and the increased physical activity accompanied improved QoL. Depression and fatigue were related to impaired QoL).
Harri Sievänen, Research Director
Saarto T, Penttinen HM, Sievänen H, Kellokumpu-Lehtinen PL, Hakamies-Blomqvist L, Nikander R, Huovinen R, Luoto R, Kautiainen H, Järvenpää S, Idman I, Utriainen M, Vehmanen L, Jääskeläinen AS, Elme A, Ruohola J, Palva T, Vertio H, Rautalahti M, Fogelholm M, Blomqvist C, Luoma ML. Effectiveness of a 12-month exercise program on physical performance and quality of life of breast cancer survivors. Anticancer Res. 2012;32:3875-84.
Nikander R, Sievänen H, Ojala K, Kellokumpu-Lehtinen PL, Palva T, Blomqvist C, Luoto R, Saarto T. Effect of exercise on bone structural traits, physical performance and body composition in breast cancer patients--a 12-month RCT. J Musculoskelet Neuronal Interact. 2012;12:127-35.
Saarto T, Sievänen H, Kellokumpu-Lehtinen P, Nikander R, Vehmanen L, Huovinen R, Kautiainen H, Järvenpää S, Penttinen HM, Utriainen M, Jääskeläinen AS, Elme A, Ruohola J, Palva T, Vertio H, Rautalahti M, Fogelholm M, Luoto R, Blomqvist C. Effect of supervised and home exercise training on bone mineral density among breast cancer patients. A 12-month randomised controlled trial. Osteoporos Int. 2012 May;23(5):1601-12.
Penttinen HM, Saarto T, Kellokumpu-Lehtinen P, Blomqvist C, Huovinen R, Kautiainen H, Järvenpää S, Nikander R, Idman I, Luoto R, Sievänen H, Utriainen M, Vehmanen L, Jääskeläinen AS, Elme A, Ruohola J, Luoma M, Hakamies-Blomqvist L. Quality of life and physical performance and activity of breast cancer patients after adjuvant treatments. Psychooncology. 2011;20:1211-20.
Nikander R, Sievänen H, Ojala K, Oivanen T, Kellokumpu-Lehtinen PL, Saarto T. Effect of a vigorous aerobic regimen on physical performance in breast cancer patients - a randomized controlled pilot trial. Acta Oncol. 2007;46(2):181-6.
Updated May 2018