- Monitoring Physical Activity and Fitness
- Health-related fitness tests for public health monitoring
- Development and evaluation of a 2-km Walking Test
- Health-related fitness test battery
- Health-related fitness tests for older adults
- Required motor abilities in commonly practised exercise modes
- Physical activity and motor abilities
- Health 2000 and Health 2011
- Exercise Loading and Bone Structure
- KidsOut! — promoting physical activity and reducing sedentary behavior among 8th graders
- Physical Activity as a Medicine
- Counselling, lifestyle and physical activity in maternity care -study (NELLI)
- Effect of physical activity on menopausal symptoms
- Breast Cancer and Exercise
- KÄPY Research – Social Ecological Intervention to Promote Active Commuting to Work
- Prevention of Chronic Low Back Pain in Female Nurses
- Weight Reduction and Long-distance Truck and Bus Drivers
- Physical Activity and Reducing of Headaches
- Developing physical activity counselling
- VESOTE Effective Life-style Counselling for Social and Health Care
- Safety of Physical Activity
- Predictors of Lower Extremity Injuries in Team Sports PROFITS
- Risk Factors of Injuries and Injury Prevention in Youth Football
- Floorball Injuries – Epidemiology and Prevention
- Neuromuscular Exercise and Counseling Prevent Low Back Pain
- Effects of Exercise on Physical Functioning, Bone Strength and Fall Risk among Older Women
- Vitamin D and Exercise in Fall Prevention
- Effect of Vibration Training on Physical Functioning and Risk of Falling in Older People
- Fall-induced Injuries Among Older Adults in Finland
- LiVE: Sports and Exercise Safety Program in Finland
- KaatumisSeula: Implementation of Evidence-Based Fall Prevention for Communities
- Recent Presentations in Conferences
- WHO Europe HEPA Collaboration
Vitamin D and Exercise in Fall Prevention
A 2-year randomized, controlled trial with 2-year follow-up to investigate if exercise and vitamin D supplementation could improve the performance of the neuromuscular system (muscle strength and balance) among the elderly and reduce falls and fall-related injuries.
Falls are the leading cause of unintentional injuries and fractures in older adults. Although less than one in ten falls results in a fracture, about 20 % of falls lead to injury needing medical attention. Therefore, falls prevention is widely considered the most essential element in injury and fracture prevention programs in elderly populations. While vitamin D supplementation and exercise are recommended for prevention of falls for older people, results regarding these two factors are contradictory.
In this 2-year double-blind placebo-controlled vitamin D and open exercise intervention trial with four arms we investigated the separate and combined effects of multimodal exercise training and vitamin D supplementation in reducing falls and injurious falls, and in improving bone density and physical functioning among 70–80-year old home-dwelling women at risk for falling. After the intervention there was a 2-year follow-up period.
409 participants were randomly assigned to one of four groups:
- vitamin D 800 IU/d and exercise (D+Ex+)
- placebo and exercise (D-Ex+)
- vitamin D 800 IU/d without exercise (D+Ex-)
- placebo without exercise (D-Ex-).
The exercisers participated in supervised training two times a week during the first year and once a week during the following year. In addition to the supervised training sessions, the participants did daily exercises at home.
Primary outcome was monthly reported falls. Injurious falls were reported as a secondary outcome. In addition, bone density, physical functioning (muscle strength, balance and mobility), and vitamin D metabolism were assessed.
The trial was done between April 2010 and March 2013. The 2-year follow-up ended on March 2015.
The risk for injurious falls more than halved with strength and balance training in home-dwelling older women, while neither exercise nor vitamin D affected the rate of falls. Exercise improved physical functioning. Future research is needed to determine the role of vitamin D in enhancement of strength, balance and mobility.
Clinical Trials NCT00986466
Uusi-Rasi K, Patil R, Karinkanta S, Kannus P, Tokola K, Lamberg-Allardt C, Sievänen H. A 2-year follow-up after a 2-year RCT with vitamin D and exercise: Effects on falls, injurious falls and physical functioning among older women. Journals of Gerontology. A. Medical Sciences 2017;72(9):1239-1245. doi.org/10.1093/gerona/glx044
Patil R, Karinkanta S, Tokola K, Kannus P, Sievänen H, Uusi-Rasi K. Effects of vitamin D and exercise on the wellbeing of older community-dwelling women: a randomized controlled trial. Gerontology 2016;62():401-408.
Uusi-Rasi K, Patil R, Karinkanta S, Tokola K, Kannus K, Lamberg-Allardt C, Sievänen H. Long-Term Effects of Vitamin D and Multimodal Exercise on Prevention of Injurious Falls in Older Women. A 2-year follow-up after intervention. J Bone Miner Res 31 (Suppl 1). Available at http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid=51d4e88b-f79d-47e2-a15b-134f0c57b52e. Accessed September 27, 2016.
Patil R, Kolu P, Raitanen J, Valvanne J, Kannus P, Karinkanta S, Sievänen H, Uusi-Rasi K: Cost-effectiveness of vitamin D supplementation and exercise in preventing injurious falls among older home-dwelling women: findings from an RCT. Osteoporos Int 2016; 27:193-201. Epub 2015 Jul 24. PMID: 26205890.
Uusi-Rasi K, Patil P, Karinkanta S, Kannus P, Tokola K, Lamberg-Allardt C, Sievänen H: Exercise and vitamin D in falls prevention among older women: A randomized controlled trial. JAMA Intern Med 2015; 175: 703-11. doi:10.1001/jamainternmed.2015.0225.
For all publications of this research, see the Finnish description. To find the list of publications "Julkaisuja", scroll the page down. To open the publication links, click "Lue lisaa" and "Lue julkaisu".
Updated April 2018